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br Materials and methods br
2019-11-11
Materials and methods Results Discussion Prolyl 4-hydroxylases are oxygenases with key roles in a variety of biological processes including oxygen sensing, siRNA regulation and collagen folding (Gorres and Raines, 2010). Hydroxyproline is particularly abundant in collagenous proteins which
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br Discussion Immune response to CMV is a series cell
2019-11-11
Discussion Immune response to CMV is a series cell-mediated immune response initiated by innate innate NK cells, followed by adaptive CD8+ and CD4+ T cells and humoral immunity by B cell [3]. Prior to transplant, measurement of humoral immune responses (CMV serology) of donor and recipient is com
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Interestingly selective ETA blockade increased cutaneous blo
2019-11-11
Interestingly, selective ETA blockade increased cutaneous blood flow as measured by laser Doppler fluxmetry. This is a measure of total blood flow in the different vessels in the skin including venules, IKK-16 receptor as well as arterioles. This finding is in accordance with the previous demonstra
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AVE 0991 The highest concentrations from several tens to
2019-11-11
The highest concentrations (from several tens to often hundreds or thousands ng/L) are reported in animal farm flush water, and associated runoffs and lagoons in China and in the U.S. Lower concentrations are reported in WWTP influents and effluents. In WWTP influent waters DRO, LNG, NET and PRG hav
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bungarotoxin receptor br Discussion EFTs are sarcomas with
2019-11-11
Discussion EFTs are sarcomas with almost undifferentiated histologic features, consequently their differentiation from other small, blue, round cell tumors may be difficult. Substantial intracellular bungarotoxin receptor on PAS stain is a useful diagnostic feature. The addition of CD99 and FLI1
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Our approach including the characterization of
2019-11-11
Our approach, including the characterization of histone modifications in scarce NK subsets, allowed us to identify super-enhancers, which associate with genes endowing a given cell type with its unique identity (Hnisz et al., 2013). Especially intriguing were SEs with distinct activities in NK subse
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AMPHs facilitate dopamine release which further
2019-11-11
AMPHs facilitate dopamine release, which further triggers dopamine depletion [72]. Indeed, we observed that repeated treatment of MPA significantly inhibited TH-, DAT-, and VMAT-2 levels. Since DAT and VMAT-2 are important for dopaminergic terminal markers [10], their decreases suggest that MPA-indu
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E cadherin is an adhesive Ca dependent transmembrane protein
2019-11-08
E-cadherin is an adhesive Ca2+ dependent transmembrane protein mediating tight and strong cell-cell adhesion through homophilic interactions. There is strong evidence in favour of the major role of E-cadherin in melanocytes adhesion to keratinocytes in the Carbidopa (Tang et al., 1994). The express
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SB 290157 trifluoroacetate salt DDR was originally cloned by
2019-11-08
DDR1 was originally cloned by the group of Michele de Luca, at the time named TrkE. The Genoa-based research team identified the skin, and the keratinocytes in particular, as a major site of DDR1-binding activity [20]. DDR1 is also expressed in kidney, liver and lung (Fig. 2). The functional role of
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Edrophonium chloride Pharmacogenomics is the study of the ro
2019-11-08
Pharmacogenomics is the study of the role of the Edrophonium chloride in drug response. It was reported that the effectiveness of atorvastatin was affected by genetic factors.26, 27 In previous studies, there are many genetic polymorphisms related to the efficacy of atorvastatin. Cerda et al report
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Furthermore software engineering practices are important for
2019-11-08
Furthermore, software engineering practices are important for addressing productivity problems in scientific software. Even though the speed of the hardware is rapidly increasing, the additional complexity makes it more difficult for scientists to be productive developers. According to Faulk et al.,
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All of these experiments in GM
2019-11-08
All of these experiments in GM matter injury models have identified an array of signaling mechanisms that are potentially important. First, Kim et al. proposed that CK2 acts as a negative modulator of NADPH oxidase [55]. Then Blanquet et al. [50] found that increased CK2 correlated with inhibition o
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br Materials and methods br Results
2019-11-08
Materials and methods Results and discussion Conclusions Acknowledgments This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (No. 2011-0030635) and the MarineBio Research Program (NRF-C1ABA001-2011-0018561). The Fonta
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br Multi hierarchical structure of
2019-11-08
Multi-hierarchical structure of collagen Protein structure is the foundation of protein functions and properties. It is generally accepted that the protein has biological function only when it has tertiary structure or above. Among the identified 28 types of collagen, most is known about type I c
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br Acknowledgements The authors thank Drs C Klein I
2019-11-08
Acknowledgements The authors thank Drs. C. Klein, I. Canisso and A. Claes with assistance in obtaining tissues. Supported by the Albert G. Clay Endowment, University of Kentucky. Introduction Neoplastic cells often develop drug resistance during tumor progression or cancer treatment (Turner a
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